Goeast gene ontology enrichment analysis essay.

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GO enrichment analysis. One of the main uses of the GO is to perform enrichment analysis on gene sets. For example, given a set of genes that are up-regulated under certain conditions, an enrichment analysis will find which GO terms are over-represented (or under-represented) using annotations for that gene set.

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There are many different approaches that can be used to understand the biological context of protein-protein interaction networks. Annotation enrichment analysis is one of the most popular methods. Although it is not strictly speaking a network analysis tool, it is often used in combination with topological network analysis.

I think most of the enrichment analysis tools deals with same class of statistics methods (p-value, FDR, Boneferroni etc). Defining background is a very important in such enrichment methods. To get real meaning of enrichment with respect to your experiments, you should be able to upload the background. For example, if you are looking at a set.

This review supports the idea that enrichment is an attempt to ameliorate problems caused by containment, that the goals of enrichment are to alter behaviour so that it is within the range of the animals' normal behaviour, and that evaluation of the success of enrichment techniques is important.

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